IGF-DES (0.1mg)

SKU: YPB.286 Category:

Description

A single-component research material supplied for controlled research environments. IGF-1 DES(1-3) (0.1 mg) is a truncated analog of IGF-1 lacking the first three N-terminal amino acids (Gly-Pro-Glu), resulting in significantly reduced IGF binding protein (IGFBP) affinity and enhanced receptor bioavailability, widely used in research exploring IGF-1 receptor activation, mitogenic signaling, and growth factor potency in model systems.


Composition

  • IGF-DES (IGF-1 DES(1-3)): 0.1 mg

  • Appearance: lyophilized powder in a sealed research vial


Research Focus (non-clinical)

  • Investigation of unbound IGF-1R activation kinetics and enhanced mitogenic potency compared to full-length IGF-1 in cell culture studies

  • Evaluation of IGFBP-independent proliferative responses in in vitro and in vivo experimental models

  • Assessment of autocrine and paracrine growth factor signaling in tissue-specific model systems under controlled laboratory conditions

  • Stability and bioactivity characterization of lyophilized IGF-DES under laboratory storage conditions


Documentation

  • Lot-specific COA available

  • Batch and lot traceability

Important Notice

  • For research use only

  • Not for human consumption

  • Not intended to diagnose, treat, cure, or prevent any disease


Quality & Manufacturing

  • Lot-specific COA

  • Lyophilized for transit stability; batch traceable

  • Tamper-evident seal; lot & test date on each vial

  • No MOQ for online orders

  • Bulk orders for physical locations start at 25-unit minimum